---
ticker: "FMED"
name: "Fidelity Disruptive Medicine ETF"
url: "https://etf.net/etf/FMED"
grade: "C"
score: 49
graded_at: "2026-10-12"
category: "Health Care (Broad)"
category_rank: "14 of 25"
methodology: "https://etf.net/methodology"
---

# FMED: Fidelity Disruptive Medicine ETF

Grade **C**, Score 49 of 100. Rank 14 of 25 in Health Care (Broad).

Graded Oct 12, 2026.

## Grade pillars

| Pillar | Score | Category rank |
| --- | --- | --- |
| Cost | 52 | 12 of 25 |
| Mission | 63 | 11 of 11 |
| Risk | 49 | 13 of 24 |
| Tradability | 28 | 18 of 25 |
| Holdings | 74 | 8 of 25 |
| Durability | 47 | 15 of 25 |

## Top holdings

The fund holds 75 positions. These are the largest 30, by weight.

| # | Ticker | Name | Weight |
| --- | --- | --- | --- |
| 1 | — | Securities Lending Cf | 14.11% |
| 2 | TXG | 10X Genomics Inc | 5.14% |
| 3 | NTRA | Natera Inc | 4.40% |
| 4 | TMO | Thermo Fisher Scientific Inc | 4.13% |
| 5 | DHR | Danaher Corp | 3.88% |
| 6 | ILMN | Illumina Inc | 3.71% |
| 7 | DIM.PA | Sartorius Stedim Biotech | 2.81% |
| 8 | LFST | Lifestance Health Group Inc | 2.79% |
| 9 | MRNA | Moderna Inc | 2.69% |
| 10 | RVMD | Revolution Medicines Inc | 2.68% |
| 11 | ARGX | Argenx SE Sponsored Adr | 2.59% |
| 12 | ALNY | Alnylam Pharmaceuticals Inc | 2.28% |
| 13 | ISRG | Intuitive Surgical Inc | 2.25% |
| 14 | WST | West Pharmaceutical Svcs Inc | 2.23% |
| 15 | HTFL | Heartflow Inc | 2.20% |
| 16 | PCVX | Vaxcyte Inc | 2.18% |
| 17 | GH | Guardant Health Inc | 2.13% |
| 18 | COGT | Cogent Biosciences Inc | 2.07% |
| 19 | KNSA | Kiniksa Pharmaceuticals Intern | 2.00% |
| 20 | KYMR | Kymera Therapeutics Inc | 1.87% |
| 21 | VEEV | Veeva Sys Inc Class A | 1.74% |
| 22 | ASND | Ascendis Pharma As | 1.74% |
| 23 | RGEN | Repligen | 1.71% |
| 24 | — | Roivant Sciences Ltd | 1.62% |
| 25 | TWST | Twist Bioscience Corp | 1.57% |
| 26 | INSM | Insmed Inc | 1.53% |
| 27 | UCB.BR | Ucb SA | 1.48% |
| 28 | EW | Edwards Lifesciences Corp | 1.47% |
| 29 | UNH | UnitedHealth Group Inc | 1.34% |
| 30 | AMLX | Amylyx Pharmaceuticals Inc | 1.30% |

Source: etf.net, https://etf.net/etf/FMED. Please cite the page URL.