---
ticker: "IBBQ"
name: "Invesco Nasdaq Biotechnology ETF"
url: "https://etf.net/etf/IBBQ"
grade: "A"
score: 77
graded_at: "2026-10-12"
category: "Biotech & Genomics"
category_rank: "2 of 17"
methodology: "https://etf.net/methodology"
---

# IBBQ: Invesco Nasdaq Biotechnology ETF

Grade **A**, Score 77 of 100. Rank 2 of 17 in Biotech & Genomics.

Graded Oct 12, 2026.

## Grade pillars

| Pillar | Score | Category rank |
| --- | --- | --- |
| Cost | 100 | 1 of 17 |
| Mission | 84 | 4 of 9 |
| Risk | 72 | 3 of 17 |
| Tradability | 46 | 10 of 17 |
| Holdings | 62 | 8 of 17 |
| Durability | 39 | 14 of 17 |

## Top holdings

The fund holds 250 positions. These are the largest 30, by weight.

| # | Ticker | Name | Weight |
| --- | --- | --- | --- |
| 1 | GILD | Gilead Sciences Inc | 8.41% |
| 2 | AMGN | Amgen Inc | 7.87% |
| 3 | VRTX | Vertex Pharmaceuticals Inc | 7.63% |
| 4 | MRNA | Moderna Inc | 5.99% |
| 5 | REGN | Regeneron Pharmaceuticals Inc | 5.03% |
| 6 | ILMN | Illumina Inc | 2.80% |
| 7 | RVMD | Revolution Medicines Inc | 2.71% |
| 8 | BIIB | Biogen Inc | 2.22% |
| 9 | ALNY | Alnylam Pharmaceuticals Inc | 2.08% |
| 10 | ROIV | Roivant Sciences Ltd | 1.71% |
| 11 | RPRX | Royalty Pharma PLC | 1.69% |
| 12 | UTHR | United Therapeutics Corp | 1.57% |
| 13 | INCY | Incyte Corp | 1.52% |
| 14 | GH | Guardant Health Inc | 1.50% |
| 15 | ARGNF | Argenx SE | 1.49% |
| 16 | INSM | Insmed Inc | 1.46% |
| 17 | VTRS | Viatris Inc | 1.35% |
| 18 | MEDP | Medpace Holdings Inc | 1.13% |
| 19 | EXEL | Exelixis Inc | 0.99% |
| 20 | NBIX | Neurocrine Biosciences Inc | 0.96% |
| 21 | JAZZ | Jazz Pharmaceuticals PLC | 0.94% |
| 22 | ASND | Ascendis Pharma A/S | 0.94% |
| 23 | SMMT | Summit Therapeutics Inc | 0.94% |
| 24 | BBIO | Bridgebio Pharma Inc | 0.87% |
| 25 | ONC | BeOne Medicines Ltd | 0.84% |
| 26 | HALO | Halozyme Therapeutics Inc | 0.83% |
| 27 | TEM | Tempus AI Inc | 0.83% |
| 28 | BNTX | BioNTech SE | 0.75% |
| 29 | IBRX | ImmunityBio Inc | 0.74% |
| 30 | MDGL | Madrigal Pharmaceuticals Inc | 0.72% |

Source: etf.net, https://etf.net/etf/IBBQ. Please cite the page URL.