---
ticker: "IBRN"
name: "iShares Neuroscience and Healthcare ETF"
url: "https://etf.net/etf/IBRN"
grade: "C"
score: 44
graded_at: "2026-10-12"
category: "Biotech & Genomics"
category_rank: "10 of 17"
methodology: "https://etf.net/methodology"
---

# IBRN: iShares Neuroscience and Healthcare ETF

Grade **C**, Score 44 of 100. Rank 10 of 17 in Biotech & Genomics.

Graded Oct 12, 2026.

## Grade pillars

| Pillar | Score | Category rank |
| --- | --- | --- |
| Cost | 56 | 7 of 17 |
| Mission | Not scored | — |
| Risk | 28 | 15 of 17 |
| Tradability | 28 | 14 of 17 |
| Holdings | 62 | 8 of 17 |
| Durability | 31 | 15 of 17 |

## Top holdings

The fund holds 79 positions. These are the largest 30, by weight.

| # | Ticker | Name | Weight |
| --- | --- | --- | --- |
| 1 | BIIB | Biogen | 4.96% |
| 2 | PTCT | Ptc Therapeutics | 4.53% |
| 3 | NBIX | Neurocrine Biosciences | 4.44% |
| 4 | EWTX | Edgewise Therapeutics | 4.40% |
| 5 | ALKS | Alkermes | 4.28% |
| 6 | ARGX | Argenx SE Adr | 3.89% |
| 7 | SRRK | Scholar Rock Holding | 3.70% |
| 8 | DNTH | Dianthus Therapeutics Inc | 3.69% |
| 9 | PRAX | Praxis Precision Medicines | 3.58% |
| 10 | SUPN | Supernus Pharmaceuticals | 3.56% |
| 11 | ACAD | Acadia Pharmaceuticals | 3.43% |
| 12 | DYN | Dyne Therapeutics | 3.32% |
| 13 | 326030.KS | Sk Biopharmaceuticals Ltd | 3.25% |
| 14 | XENE | Xenon Pharmaceuticals | 2.96% |
| 15 | AXGN | Axogen | 2.90% |
| 16 | HLUN-B.CO | H. Lundbeck Class B | 2.83% |
| 17 | SRPT | Sarepta Therapeutics | 2.76% |
| 18 | BHVN | Biohaven | 2.38% |
| 19 | NEU.AX | Neuren Pharmaceuticals | 2.37% |
| 20 | BIOA-B.ST | Bioarctic Class B | 1.93% |
| 21 | TSHA | Taysha Gene Therapies | 1.82% |
| 22 | LBRX | Lb Pharmaceuticals Inc | 1.51% |
| 23 | 4588.T | Oncolys Biopharma Inc | 1.48% |
| 24 | IDIA.SW | Idorsia N Ltd | 1.45% |
| 25 | IART | Integra Lifesciences Holdings | 1.37% |
| 26 | RAPP | Rapport Therapeutics | 1.35% |
| 27 | ANRO | Alto Neuroscience Inc | 1.32% |
| 28 | — | Rubicon Research | 1.26% |
| 29 | DYVOX.ST | Dynavox Group | 1.26% |
| 30 | MEDCL.PA | Medincell SA | 1.18% |

Source: etf.net, https://etf.net/etf/IBRN. Please cite the page URL.