---
ticker: "LABU"
name: "Direxion Daily S&P Biotech Bull 3X Shares"
url: "https://etf.net/etf/LABU"
grade: "B"
score: 64
graded_at: "2026-10-12"
category: "3x Leveraged Long"
category_rank: "8 of 31"
methodology: "https://etf.net/methodology"
---

# LABU: Direxion Daily S&P Biotech Bull 3X Shares

Grade **B**, Score 64 of 100. Rank 8 of 31 in 3x Leveraged Long.

Graded Oct 12, 2026.

## Grade pillars

| Pillar | Score | Category rank |
| --- | --- | --- |
| Cost | 73 | 6 of 31 |
| Mission | Not scored | — |
| Risk | 46 | 17 of 30 |
| Tradability | 67 | 7 of 31 |
| Holdings | Not scored | — |
| Durability | 59 | 10 of 31 |

## Top holdings

The fund holds 168 positions. These are the largest 30, by weight.

| # | Ticker | Name | Weight |
| --- | --- | --- | --- |
| 1 | — | Spsibi Swap Asset Leg (Spsibictl) | 20.18% |
| 2 | — | Spsibi Swap Asset Leg (Spsibiubl) | 14.78% |
| 3 | — | Spsibi Swap Asset Leg (Spsibimll) | 13.46% |
| 4 | — | Spsibi Swap Asset Leg (Spsibibcl) | 10.69% |
| 5 | — | Spsibi Swap Asset Leg (Spsibijpl) | 9.06% |
| 6 | — | Goldman Finl Sq Trsry Inst 506 | 6.19% |
| 7 | — | Spsibi Swap Asset Leg (Spsibibpl) | 1.22% |
| 8 | — | Spsibi Swap Asset Leg (Spsibigsl) | 0.80% |
| 9 | — | Dreyfus Govt Cash Man Ins | 0.64% |
| 10 | MRNA | Moderna Inc | 0.56% |
| 11 | TWST | Twist Bioscience Corp | 0.43% |
| 12 | NTRA | Natera Inc | 0.41% |
| 13 | IOVA | Iovance Biotherapeutics Inc | 0.38% |
| 14 | ABBV | AbbVie Inc | 0.37% |
| 15 | UTHR | United Therapeutics Corp | 0.36% |
| 16 | BIIB | Biogen Inc | 0.36% |
| 17 | AMGN | Amgen Inc | 0.36% |
| 18 | GILD | Gilead Sciences Inc | 0.35% |
| 19 | HALO | Halozyme Therapeutics Inc | 0.35% |
| 20 | EXEL | Exelixis Inc | 0.35% |
| 21 | TGTX | Tg Therapeutics Inc | 0.34% |
| 22 | PTGX | Protagonist Therapeutics Inc | 0.33% |
| 23 | SYRE | Spyre Therapeutics Inc | 0.33% |
| 24 | CRSP | Crispr Therapeutics AG | 0.33% |
| 25 | VRTX | Vertex Pharmaceuticals Inc | 0.33% |
| 26 | PCVX | Vaxcyte Inc | 0.32% |
| 27 | PTCT | Ptc Therapeutics Inc | 0.32% |
| 28 | KRYS | Krystal Biotech Inc | 0.32% |
| 29 | GRAL | Grail Inc | 0.32% |
| 30 | REGN | Regeneron Pharmaceuticals | 0.31% |

Source: etf.net, https://etf.net/etf/LABU. Please cite the page URL.