---
ticker: "MMSC"
name: "First Trust Multi-Manager Small Cap Opportunities ETF"
url: "https://etf.net/etf/MMSC"
grade: "D"
score: 28
graded_at: "2026-10-12"
category: "US Active Small-Cap"
category_rank: "33 of 41"
methodology: "https://etf.net/methodology"
---

# MMSC: First Trust Multi-Manager Small Cap Opportunities ETF

Grade **D**, Score 28 of 100. Rank 33 of 41 in US Active Small-Cap.

Graded Oct 12, 2026.

## Grade pillars

| Pillar | Score | Category rank |
| --- | --- | --- |
| Cost | 5 | 39 of 41 |
| Mission | 73 | 6 of 10 |
| Risk | 20 | 36 of 38 |
| Tradability | 54 | 19 of 41 |
| Holdings | 55 | 23 of 41 |
| Durability | 71 | 10 of 41 |

## Top holdings

The fund holds 203 positions. These are the largest 30, by weight.

| # | Ticker | Name | Weight |
| --- | --- | --- | --- |
| 1 | XMTR | Xometry, Inc. (Class A) | 1.96% |
| 2 | TWST | Twist Bioscience Corporation | 1.71% |
| 3 | FROG | JFrog Ltd. | 1.68% |
| 4 | ZETA | Zeta Global Holdings Corp. (Class A) | 1.54% |
| 5 | RGEN | Repligen Corporation | 1.41% |
| 6 | FCFS | FirstCash Holdings, Inc. | 1.40% |
| 7 | GH | Guardant Health, Inc. | 1.34% |
| 8 | VRNS | Varonis Systems, Inc. | 1.33% |
| 9 | TVTX | Travere Therapeutics, Inc. | 1.28% |
| 10 | PTGX | Protagonist Therapeutics, Inc. | 1.20% |
| 11 | SAIL | SailPoint, Inc. | 1.20% |
| 12 | RBRK | Rubrik, Inc. (Class A) | 1.14% |
| 13 | LGND | Ligand Pharmaceuticals Inc. (Class B) | 1.04% |
| 14 | SIMO | Silicon Motion Technology Corporation (ADR) | 1.02% |
| 15 | SYRE | Spyre Therapeutics, Inc. | 1.00% |
| 16 | HALO | Halozyme Therapeutics, Inc. | 0.99% |
| 17 | FSLY | Fastly, Inc. (Class A) | 0.95% |
| 18 | EZPW | EZCORP, Inc. | 0.92% |
| 19 | VSEC | VSE Corporation | 0.89% |
| 20 | OLLI | Ollie's Bargain Outlet Holdings, Inc. | 0.84% |
| 21 | EXEL | Exelixis, Inc. | 0.84% |
| 22 | DOCN | DigitalOcean Holdings, Inc. | 0.79% |
| 23 | MTSI | MACOM Technology Solutions Holdings, Inc. | 0.77% |
| 24 | MANH | Manhattan Associates, Inc. | 0.77% |
| 25 | PRAX | Praxis Precision Medicines, Inc. | 0.77% |
| 26 | EWTX | Edgewise Therapeutics, Inc. | 0.77% |
| 27 | DFTX | Definium Therapeutics Inc. | 0.75% |
| 28 | MXL | MaxLinear, Inc. | 0.75% |
| 29 | VIRT | Virtu Financial, Inc. (Class A) | 0.73% |
| 30 | RBC | RBC Bearings Incorporated | 0.72% |

Source: etf.net, https://etf.net/etf/MMSC. Please cite the page URL.