---
ticker: "OZEM"
name: "Roundhill Investments - GLP-1 & Weight Loss ETF"
url: "https://etf.net/etf/OZEM"
grade: "C"
score: 43
graded_at: "2026-10-12"
category: "Pharma & Therapeutics"
category_rank: "7 of 9"
methodology: "https://etf.net/methodology"
---

# OZEM: Roundhill Investments - GLP-1 & Weight Loss ETF

Grade **C**, Score 43 of 100. Rank 7 of 9 in Pharma & Therapeutics.

Graded Oct 12, 2026.

## Grade pillars

| Pillar | Score | Category rank |
| --- | --- | --- |
| Cost | 41 | 5 of 9 |
| Mission | 67 | 4 of 6 |
| Risk | 20 | 8 of 9 |
| Tradability | 29 | 7 of 9 |
| Holdings | 52 | 6 of 9 |
| Durability | 42 | 7 of 9 |

## Top holdings

The fund holds 27 positions. These are the largest 27, by weight.

| # | Ticker | Name | Weight |
| --- | --- | --- | --- |
| 1 | LLY | Eli Lilly & Co | 13.60% |
| 2 | NVO | Novo Nordisk A/S | 11.84% |
| 3 | PFE | Pfizer Inc | 8.03% |
| 4 | 1093.HK | CSPC Pharmaceutical Group Ltd | 6.13% |
| 5 | KLRA | Kailera Therapeutics Inc | 5.38% |
| 6 | VKTX | Viking Therapeutics Inc | 4.99% |
| 7 | 4519.T | Chugai Pharmaceutical Co Ltd | 4.66% |
| 8 | AMGN | Amgen Inc | 4.54% |
| 9 | 128940.KS | Hanmi Pharm Co Ltd | 4.38% |
| 10 | AZN | AstraZeneca PLC | 3.89% |
| 11 | 1672.HK | Ascletis Pharma Inc | 3.77% |
| 12 | ZEAL.CO | Zealand Pharma A/S | 3.52% |
| 13 | ROP.SW | Roche Holding AG | 3.36% |
| 14 | 1276.HK | Jiangsu Hengrui Pharmaceuticals Co Ltd | 2.86% |
| 15 | 3933.HK | United Laboratories International Holdings Ltd/The | 2.82% |
| 16 | 3692.HK | Hansoh Pharmaceutical Group Co Ltd | 2.66% |
| 17 | 1801.HK | Innovent Biologics Inc | 2.43% |
| 18 | GUBRA.CO | Gubra A/S | 2.16% |
| 19 | GPCR | Structure Therapeutics Inc | 1.98% |
| 20 | GILD | Gilead Sciences Inc | 1.95% |
| 21 | MBX | MBX Biosciences Inc | 1.94% |
| 22 | RYTM | Rhythm Pharmaceuticals Inc | 1.45% |
| 23 | 4507.T | Shionogi & Co Ltd | 1.32% |
| 24 | FGXXX | First American Government Obligations Fund 12/01/2031 | 0.34% |
| 25 | WVE | Wave Life Sciences Inc | 0.27% |
| 26 | — | Cash & Other | 0.21% |
| 27 | JPY | Japanese Yen | <0.01% |

Source: etf.net, https://etf.net/etf/OZEM. Please cite the page URL.