---
ticker: "PILL"
name: "Direxion Daily Pharmaceutical & Medical Bull 3X ETF"
url: "https://etf.net/etf/PILL"
grade: "D"
score: 26
graded_at: "2026-10-12"
category: "3x Leveraged Long"
category_rank: "28 of 31"
methodology: "https://etf.net/methodology"
---

# PILL: Direxion Daily Pharmaceutical & Medical Bull 3X ETF

Grade **D**, Score 26 of 100. Rank 28 of 31 in 3x Leveraged Long.

Graded Oct 12, 2026.

## Grade pillars

| Pillar | Score | Category rank |
| --- | --- | --- |
| Cost | 13 | 27 of 31 |
| Mission | Not scored | — |
| Risk | 56 | 12 of 30 |
| Tradability | 25 | 28 of 31 |
| Holdings | Not scored | — |
| Durability | 22 | 29 of 31 |

## Top holdings

The fund holds 67 positions. These are the largest 30, by weight.

| # | Ticker | Name | Weight |
| --- | --- | --- | --- |
| 1 | — | Spsiph Swap Asset Leg (Spsiphctl) | 32.61% |
| 2 | — | Spsiph Swap Asset Leg (Spsiphubl) | 16.31% |
| 3 | — | Spsiph Swap Asset Leg (Spsiphjpl) | 11.08% |
| 4 | — | Spsiph Swap Asset Leg (Spsiphbcl) | 8.42% |
| 5 | — | Goldman Finl Sq Trsry Inst 506 | 7.30% |
| 6 | — | Dreyfus Govt Cash Man Ins | 1.36% |
| 7 | XERS | Xeris Biopharma Holdings Inc | 0.62% |
| 8 | MANE | Veradermics Inc | 0.60% |
| 9 | PCRX | Pacira Biosciences Inc | 0.58% |
| 10 | AMRX | Amneal Pharmaceuticals Inc | 0.53% |
| 11 | VTRS | Viatris Inc | 0.49% |
| 12 | PRGO | Perrigo Co PLC | 0.48% |
| 13 | CORT | Corcept Therapeutics Inc | 0.48% |
| 14 | LGND | Ligand Pharmaceuticals | 0.48% |
| 15 | LLY | Eli Lilly & Co | 0.48% |
| 16 | ANIP | Ani Pharmaceuticals Inc | 0.48% |
| 17 | INDV | Indivior Pharmaceuticals Inc | 0.47% |
| 18 | OMER | Omeros Corp | 0.47% |
| 19 | ZTS | Zoetis Inc | 0.47% |
| 20 | PFE | Pfizer Inc | 0.47% |
| 21 | SUPN | Supernus Pharmaceuticals Inc | 0.47% |
| 22 | OGN | Organon & Co | 0.46% |
| 23 | INVA | Innoviva Inc | 0.46% |
| 24 | PBH | Prestige Consumer Healthcare | 0.45% |
| 25 | MRK | Merck & Co. Inc. | 0.45% |
| 26 | MAZE | Maze Therapeutics Inc | 0.45% |
| 27 | JNJ | Johnson & Johnson | 0.45% |
| 28 | ELAN | Elanco Animal Health Inc | 0.45% |
| 29 | DFTX | Definium Therapeutics, Inc | 0.45% |
| 30 | HRMY | Harmony Biosciences Holdings | 0.44% |

Source: etf.net, https://etf.net/etf/PILL. Please cite the page URL.