---
ticker: "TBXU"
name: "Direxion Daily Biotech Top 5 Bull 2X ETF"
url: "https://etf.net/etf/TBXU"
grade: "D"
score: 27
graded_at: "2026-10-12"
category: "Leveraged Long (2x & Other)"
category_rank: "87 of 99"
methodology: "https://etf.net/methodology"
---

# TBXU: Direxion Daily Biotech Top 5 Bull 2X ETF

Grade **D**, Score 27 of 100. Rank 87 of 99 in Leveraged Long (2x & Other).

Graded Oct 12, 2026.

## Grade pillars

| Pillar | Score | Category rank |
| --- | --- | --- |
| Cost | 2 | 97 of 99 |
| Mission | Not scored | — |
| Risk | 62 | 30 of 96 |
| Tradability | 38 | 67 of 99 |
| Holdings | Not scored | — |
| Durability | 41 | 63 of 99 |

## Top holdings

The fund holds 11 positions. These are the largest 11, by weight.

| # | Ticker | Name | Weight |
| --- | --- | --- | --- |
| 1 | — | BIOEW5 Swap Asset Leg (BIOEW5BCL) | 21.88% |
| 2 | — | BIOEW5 Swap Asset Leg (BIOEW5MLL) | 19.93% |
| 3 | — | BIOEW5 Swap Asset Leg (BIOEW5CTL) | 15.33% |
| 4 | — | Dreyfus Govt Cash Man Ins | 13.08% |
| 5 | AMGN | Amgen Inc | 5.06% |
| 6 | GILD | Gilead Sciences Inc | 4.84% |
| 7 | VRTX | Vertex Pharmaceuticals Inc | 4.56% |
| 8 | — | Goldman Finl Sq Trsry Inst 506 | 4.52% |
| 9 | REGN | Regeneron Pharmaceuticals | 4.40% |
| 10 | ARGX | Argenx SE - Adr | 3.85% |
| 11 | — | Goldman Sachs Fin Gov 465 Institut | 2.57% |

Source: etf.net, https://etf.net/etf/TBXU. Please cite the page URL.