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Roundhill Investments - GLP-1 & Weight Loss ETF

OZEMNasdaqC

$28.89−0.47 (−1.60%)

At close: Oct 13, 2026, 4:00 PM

Intraday session: down, 59 prints from 29.36 to 28.89. Range 28.85 to 29.35. Use the arrow keys to read each point.29.0029.1029.2029.3010 AM12 PM2 PM4 PM
Expense ratio
0.59%
Fund size
$55M
1Y total return
+3.7%
Yield · Last 12 months
1.40%
Holdings
27
Avg volume · 30D
0M sh
NAV per share
$29.56
52W range
low $27.34high $37.15
Launched

The ETF.net OZEM Grade

C

Score 43 out of 100

Rank
7 of 9
Six-pillar profile for OZEM. Scores out of 100: Cost 41, Risk 20, Mission 67, Tradability 29, Holdings 52, Durability 42. Strongest: Mission (67). Weakest: Risk (20). Leans toward Mission.

Score 43 of 100 falls in the C band. A is 70 or higher, B 55 to under 70, C 40 to under 55, D 25 to under 40, F under 25.

  • Cost

    The fund’s net expense ratio, ranked against its category.
    C41 out of 100
    Rank 5 of 9
  • Mission

    Whether the fund did what it promised, tested against its stated mandate.
    B67 out of 100
    Rank 4 of 6
  • Risk

    How the fund held up when markets fell: downside volatility, drawdowns and tail loss.
    F20 out of 100
    Rank 8 of 9
  • Tradability

    How easy the fund is to trade: daily volume, and how far its price strays from net asset value.
    D29 out of 100
    Rank 7 of 9
  • Holdings

    How concentrated the fund is, and how complete and current its disclosed holdings are.
    C52 out of 100
    Rank 6 of 9
  • Durability

    Whether the fund is likely to stay open, judged by its age, its assets and its issuer’s assets.
    C42 out of 100
    Rank 7 of 9

Our read on OZEM

ETF.net Research

CThe whole weight-loss trade in one ticker: roughly 30 stocks covering the drugmakers behind GLP-1 treatments plus the companies expected to benefit as use widens. Broad pharma funds bury this theme. OZEM is built entirely around it.

Stated mandate

The Fund seeks capital appreciation by providing exposure to companies developing pharmaceutical drugs for weight loss and anti-obesity, including GLP-1 treatments, as well as companies expected to benefit from their wider use.

Why people hold it

  1. 01The mandate is explicit: companies developing weight-loss and anti-obesity drugs, including GLP-1s, plus firms expected to benefit from wider use. No hedging into general pharma.
  2. 02A roughly 30-stock lineup means the theme actually drives the fund, rather than sitting as a small sleeve inside a diversified pharma basket.
  3. 03At 0.59%, the fee sits in the same neighborhood as established pharma funds like PJP (0.57%) and FTXH (0.60%), despite the narrower, more specialized mandate.

Worth knowing

  1. 01Broad pharma alternatives are cheaper: XPH at 0.35% and PPH at 0.36%. The theme focus here carries a price.
  2. 02Thinly traded with a modest asset base, so spreads can be wide. Limit orders are the standard tool for funds in this range.
  3. 03Launched in 2024, so the history is short, and a 30-stock single-theme basket swings on trial results and regulatory news at a handful of companies.

OZEM Holdings

As of Oct 13, 2026
Asset class
Stocks
Holdings
27
Top-10 weight
67%
Largest holding
LLY13.6%

Sectors

  • Health Care100.0%

Geography

  • United States43.30%
  • China18.64%
  • Denmark17.42%
  • Japan6.10%
  • South Korea4.44%
  • United Kingdom3.92%
  • Switzerland3.31%
  • Hong Kong2.87%

Developed 59% · Emerging 41% of the foreign sleeve

The fund’s holdings, weight-ordered — page 1 of 2.
#TickerCompanyWeight %SharesMarket valueIn ETFs
001LLYEli Lilly & Co13.60%6,323$7M583
002NVONovo Nordisk A/S11.84%168,720$7M33
003PFEPfizer Inc8.03%155,443$4M378
0041093.HKCSPC Pharmaceutical Group Ltd6.13%2,930,000$3M80
005KLRAKailera Therapeutics Inc5.38%260,799$3M51
006VKTXViking Therapeutics Inc4.99%96,697$3M92
0074519.TChugai Pharmaceutical Co Ltd4.66%67,500$3M134
008AMGNAmgen Inc4.54%5,971$2M491
009128940.KSHanmi Pharm Co Ltd4.38%6,768$2M44
010AZNAstraZeneca PLC3.89%13,509$2M72
0111672.HKAscletis Pharma Inc3.77%2,375,000$2M21
012ZEAL.COZealand Pharma A/S3.52%55,165$2M53
013ROP.SWRoche Holding AG3.36%4,286$2M199
0141276.HKJiangsu Hengrui Pharmaceuticals Co Ltd2.86%261,600$2M20
0153933.HKUnited Laboratories International Holdings Ltd/The2.82%1,644,000$2M48

Showing 1–15 of 27 holdings

OZEM Performance

Launched May 21, 2024

Shows how $10,000 changes over the selected period, with cash distributions reinvested at the closing price on each ex-dividend date.

Not enough history yet.Not enough history yet.Not enough history yet.
OZEM$10,373
SPY tracks large US stocks. It provides market context, rather than representing this fund’s strategy, asset class or investment benchmark.$12,044
Oct 10, 2025 to Oct 12, 2026. OZEM $10,373. SPY $12,044. Use the arrow keys to read each point.$9,331$11,323$13,316Oct 2025Apr 2026Oct 2026

Oct 10, 2025 – Oct 12, 2026

Returns run to the Oct 12, 2026 close, with cash distributions reinvested. Each period starts on the same date that many months or years earlier. Periods over one year show the average yearly return.

Trailing total return for OZEM. Periods over one year show the average yearly return.
PeriodOZEM
Year to date−14.1%
1 month−5.7%
3 months−11.4%
1 year+3.7%
3 yearsFund is under 3 years oldper year—
5 yearsFund is under 5 years oldper year—
10 yearsFund is under 10 years oldper year—

As of the close, with distributions reinvested.

Calendar-year total return with cash distributions hypothetically reinvested at the ex-dividend date’s closing price. The current year shows year to date.

Annual total returns for OZEM
YearReturn barOZEM
2026 YTD−14.1%
2025+41.9%
2024−3.8%

Since listing, May 21, 2024

OZEM in the news

Filtered to OZEM · Pharma & Therapeutics

OZEM Dividends

Adds up every distribution paid per share over the last 12 months, divided by the last completed close. Distributions are counted by ex-date. Data through Oct 12, 2026.
1.40%Last 12 months
Payout per share
$0.41Last 12 months
Last payment
$0.41 per share
Paid on
Shares bought on or after this date do not qualify for this distribution.
Frequency
Irregular

Distribution history

2024–2026

One bar per payment. 2 payments from 2024 to 2026 YTD. Dec 30, 2024 $0.05; Dec 30, 2025 $0.41. Use the arrow keys to read each point.202420252026YTD
Ex-datePay dateAmount per share
Dec 30, 2025Dec 31, 2025$0.41
Dec 30, 2024Dec 31, 2024$0.05

OZEM Risk

How much the fund’s monthly returns vary, scaled to a year.
20.1%
Annualised · 28 months to Sep 2026
How it’s calculated: standard deviation

The sample standard deviation of monthly total returns, multiplied by the square root of 12.

Uses up to 36 complete months, with at least 12 required. Total returns include reinvested distributions.

Return above 3-month US Treasury bills per unit of volatility.
0.36
vs 3-month T-bills · 28 months to Sep 2026
How it’s calculated: Sharpe ratio

Subtract each month’s Treasury-bill return from the fund’s monthly total return.

Divide the average of those excess returns by their sample standard deviation, then multiply by the square root of 12.

Uses up to 36 complete months, with at least 12 required. Each month uses the Treasury yield quoted at the end of the previous month.

The largest fall from a peak to the low that followed.
−28.6%
28 months · trough Apr 2025
How it’s calculated: maximum drawdown

The largest percentage decline from an earlier peak, using total returns with reinvested distributions.

Uses up to five years through the last close, with at least 12 months required.

How strongly the fund’s returns move with its asset-class index.
0.47
vs its asset-class index
How it’s calculated: beta

The beta figure is supplied by FMP. The comparison index depends on the fund’s broad asset class.

OZEM Cost

Expense ratio0.59%
  • The middle half of Pharma & Therapeutics funds
  • Median 0.58%

5 of the 9 Pharma & Therapeutics funds charge less.

OZEM costs $59.00 a year on $10,000. The median Pharma & Therapeutics fund costs $58.00.

Other funds in Pharma & Therapeutics