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MEDX vs PSR

Horizon Kinetics Medical ETF

MEDXDNasdaq

Invesco Active U.S. Real Estate ETF

PSRANYSE Arca

Overlap

Expense ratio

PSR −0.50pt a year

MEDX0.85%PSR0.35%

Avg volume · 30D

MEDX 1.3×the volume

MEDX1.88KPSR1.45K

3Y return · a year

MEDX +2.6pt

MEDX+14.1%PSR+11.5%

MEDX vs PSR Performance

Oct 31, 2025 – Nov 2, 2026

+23.4%MEDX+14.9%PSR

Oct 31, 2025 to Nov 2, 2026. MEDX +23.4%. PSR +14.9%. Use the arrow keys to read each point.0%5%10%20%Oct 2025May 2026Nov 2026
Expense ratio
MEDX 0.85%
PSR 0.35%, better
Fund size
MEDX $18M
PSR $57M
1Y total return
MEDX +23.4%, better
PSR +14.9%
Yield (12M)
MEDX 1.07%
PSR 2.67%, better
Holdings
MEDX 33
PSR 38
Avg volume (30D)
MEDX 1.88K sh, better
PSR 1.45K sh
NAV per share
MEDX $38.03
PSR $100.85
52W range

ETF.net Grade

MEDX: Cost 19, Risk 54, Mission not scored, Tradability 21, Holdings 27, Durability 45. PSR: Cost 85, Risk 57, Mission not scored, Tradability 58, Holdings 66, Durability 75.
Pillar letters and Scores for MEDX, PSR, with each pillar’s weight
PillarMEDXPSR
Cost30% weightF19A85Higher
Mission25% weightNot scoredNot scored
Risk15% weightC54B57Higher
Tradability15% weightF21B58Higher
Holdings10% weightD27B66Higher
Durability5% weightC45A75Higher

Rank among US Active Sector funds

Same Category. Both funds are graded against the same funds, so their Grades compare head to head.

Same Category. MEDX and PSR are both graded against the same 35 US Active Sector funds, so their Grades compare head to head.

US Active Sector⁠

Category · 35 funds
See all 35 ›

PSR ranks 2nd and MEDX 32nd of 35 funds in the US Active Sector Category.

  1. Rank 1AAVREAvantis Real Estate ETFScore 77
  2. Rank 2APSRInvesco Active U.S. Real Estate ETFScore 70
  3. Rank 2ATMEDT. Rowe Price Health Care ETFScore 70
  4. Rank 32DKQQQKurv Technology Titans Select ETFScore 29
  5. Rank 32DMEDXHorizon Kinetics Medical ETFScore 29
  6. Rank 34FGABFGabelli Financial Services Opportunities ETFScore 24

Our read on each fund

ETF.net Research

MEDXDHorizon Kinetics Medical ETF

PSRAInvesco Active U.S. Real Estate ETF

In short

MEDX Most healthcare funds chase drugmakers' profits. MEDX aims at the bill itself: pre-expense returns that generally track the U.S. healthcare cost inflation rate, held in a concentrated, actively run book.

PSR Active REIT stock-picking without the active price tag: since 2008, PSR has run a tight book of about 30 US property names for 0.35% a year, roughly half the median fee among active US equity ETFs.

Stated mandate

MEDX The Fund seeks to provide long-term growth of capital.

PSR The Fund seeks high total return through capital appreciation and current income, investing principally in equity real estate investment trusts.

Why people hold it

  • MEDX Unusual mandate: the fund seeks pre-expense returns that generally track the U.S. healthcare cost inflation rate, not the price of the healthcare sector.
  • Concentrated by design, roughly 30 positions. You can read the whole portfolio in a sitting instead of owning a sector index tail.
  • Actively managed by Horizon Kinetics since its 2023 launch, so the book is picked against the inflation goal rather than assembled by market cap.
  • PSR 0.35% a year against a 0.65% median for active US equity ETFs. Active management without the usual active-management markup.
  • Running since 2008, across multiple rate regimes and property cycles, and it sits in the upper half of its active US equity peer group.
  • Concentrated by design: about 30 equity REITs, so each holding carries real weight instead of being diluted across the entire property market.invesco.com
  • The mandate targets capital appreciation plus current income from equity REITs, and the fund distributes quarterly.invesco.com

Worth knowing

  • MEDX At 0.85% a year, it costs more than the median active US equity fund (0.65%), and multiples of broad core rivals like DFAU (0.12%) and FELC (0.18%).
  • Small asset base and light trading volume. Spreads can widen, so limit orders do real work here.
  • Distributions arrive once or twice a year, and against hundreds of active US equity peers it sits in the bottom quartile on our overall review.
  • PSR Thinly traded. Spreads can widen and larger orders can move the price more than they would in a heavily traded index fund.
  • One sector, one economy: US property. When rates jolt REITs, the portfolio has no other sector to lean on.
  • Assets stay modest next to the giant index REIT funds, and smaller ETFs generally face a higher bar to stay open over the long haul.

Full MEDX profile⁠

Full PSR profile⁠

MEDX vs PSR Holdings

How we measure overlap

Each holding counts at its smaller weight in the two funds, summed over the full Holdings. Sector, country and asset class use the same rule on each fund’s split. Cash, FX and derivative lines stay out of the counts. Two bond funds get no overlap figure.

MEDX vs PSR Cost

Overpaying MEDX vs PSR

$9,073

On $10,000 over 30 years. 7% growth a year before fees, expense ratio only.

  • MEDX 0.85%

    $16,199

  • PSR 0.35%

    $7,126

$10,000
30 years

Cost over time

  • MEDX 0.85%
  • PSR 0.35%
  • Overpaying
One line per fund, from year 0 to year 30. Use the arrow keys to read each point.$0$5K$10K$15K$20K051015202530MEDX $16,199PSR $7,126

Year by year

YearMEDXPSROverpaying
10$1,508$634$874
20$5,706$2,454$3,252
30$16,199$7,126$9,073

Expense ratio

  • 0.85%MEDX
  • 0.35%PSR, cheaper
  • Middle half of US Active Sector funds
  • Median 0.61%

PSR 6th cheapest of 35 funds

MEDX 28th cheapest of 35 funds

MEDX vs PSR Dividends

Last 12 months to Nov 2, 2026
Yield (12M)
MEDX 1.07%
PSR 2.67%, better
Payout (12M)
MEDX $0.41
PSR $2.72
Last payment
MEDX $0.41
PSR $0.67
Ex-dividend
MEDX Dec 23, 2025
PSR Sep 21, 2026
Paid on
MEDX Dec 24, 2025
PSR Sep 25, 2026
Frequency
MEDX Annual
PSR Quarterly

Distribution history

Per share, 2017 to 2026, same scale for both

MEDXAnnual · 3 paymentsAll MEDX payments⁠
One bar per payment. 3 payments from 2017 to 2026 YTD. Dec 27, 2023 $1.64; Dec 24, 2024 $0.51; Dec 23, 2025 $0.41. Use the arrow keys to read each point.$0$12017202020232026YTD
PSRQuarterly · 36 paymentsAll PSR payments⁠
One bar per payment. 36 payments from 2017 to 2026 YTD. Dec 18, 2017 $0.11; Mar 19, 2018 $0.30; Jun 18, 2018 $0.44; Sep 24, 2018 $0.57; Dec 24, 2018 $0.70; Mar 18, 2019 $0.16; Jun 24, 2019 $0.75; Sep 23, 2019 $0.76; Dec 23, 2019 $0.76; Mar 23, 2020 $0.70; Jun 22, 2020 $0.64; Sep 21, 2020 $0.64; Dec 21, 2020 $0.70; Mar 22, 2021 $0.60; Jun 21, 2021 $0.69; Sep 20, 2021 $0.61; Dec 20, 2021 $0.65; Mar 21, 2022 $0.63; Jun 21, 2022 $0.68; Sep 19, 2022 $0.63; Dec 19, 2022 $0.63; Mar 20, 2023 $0.65; Jun 20, 2023 $0.65; Sep 18, 2023 $0.69; Dec 18, 2023 $0.69; Mar 18, 2024 $0.69; Jun 24, 2024 $0.70; Sep 23, 2024 $0.69; Dec 23, 2024 $0.69; Mar 24, 2025 $0.56; Jun 23, 2025 $0.58; Sep 22, 2025 $0.59; Dec 22, 2025 $0.59; Mar 23, 2026 $0.67; Jun 22, 2026 $0.78; Sep 21, 2026 $0.67. Use the arrow keys to read each point.$0$12017202020232026YTD

MEDX vs PSR Risk

Fall from peak · 5 years

This chart needs five years of history for both funds.

Risk facts

VolatilityStd dev, 3 years
MEDX 15.3%, betterPSR 16.5%
Return per unit of riskSharpe ratio, 3 years
MEDX 0.71, betterPSR 0.54
Worst fallMax drawdown, 5 years
MEDX −23.1%since Feb 2023PSR −34.8%
Market sensitivityBeta, 5 years
MEDX 0.52PSR 0.95

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