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LFSC vs TMED

F/M Emerald Life Sciences Innovation ETF

LFSCBNasdaq

T. Rowe Price Health Care ETF

TMEDBNasdaq

Overlap

4.1%by weight

Expense ratio

TMED −0.10pt a year

LFSC0.54%TMED0.44%

Avg volume · 30D

TMED 1.8×the volume

LFSC4.16KTMED7.43K

LFSC vs TMED Performance

Oct 31, 2025 – Oct 30, 2026

+32.6%LFSC+20.6%TMED

Oct 31, 2025 to Oct 30, 2026. LFSC +32.6%. TMED +20.6%. Use the arrow keys to read each point.0%10%40%50%Oct 2025Apr 2026Oct 2026
Expense ratio
LFSC 0.54%
TMED 0.44%, better
Fund size
LFSC $122M
TMED $34M
1Y total return
LFSC +32.6%, better
TMED +20.6%
Holdings
LFSC 38
TMED 112
Avg volume (30D)
LFSC 4.16K sh
TMED 7.43K sh, better
NAV per share
LFSC $43.63
TMED $34.31
52W range

ETF.net Grade

LFSC: Cost 76, Risk 32, Mission 84, Tradability 61, Holdings 71, Durability 41. TMED: Cost 82, Risk 55, Mission not scored, Tradability 59, Holdings 91, Durability 35.
Pillar letters and Scores for LFSC, TMED, with each pillar’s weight
PillarLFSCTMED
Cost30% weightA76A82Higher
Mission25% weightA84Not scored
Risk15% weightD32B55Higher
Tradability15% weightB61HigherB59
Holdings10% weightA71A91Higher
Durability5% weightC41HigherD35

Rank among US Active Sector funds

How we build Categories ›
Same Category. Both funds are graded against the same funds, so their Grades compare head to head.

Same Category. LFSC and TMED are both graded against the same 35 US Active Sector funds, so their Grades compare head to head.

US Active Sector⁠

Category · 35 funds
See all 35 ›

TMED ranks 2nd and LFSC 7th of 35 funds in the US Active Sector Category.

  1. Rank 1AAVREAvantis Real Estate ETFScore 77
  2. Rank 2APSRInvesco Active U.S. Real Estate ETFScore 70
  3. Rank 2BTMEDT. Rowe Price Health Care ETFScore 70
  4. Rank 4ATRUTVanEck Technology TruSector ETFScore 69
  5. Rank 7BBMEDiShares Health Innovation Active ETFScore 61
  6. Rank 7BLFSCF/M Emerald Life Sciences Innovation ETFScore 61
  7. Rank 9BFPROFidelity Real Estate Investment ETFScore 58

Our read on each fund

ETF.net Research

LFSCBF/M Emerald Life Sciences Innovation ETF

TMEDBT. Rowe Price Health Care ETF

In short

LFSC An actively managed swing at life sciences innovation, launched in 2024 and priced below the typical active US equity fund. Healthcare stock-picking in a single ticket, not a sector index.

TMED No data

Stated mandate

LFSC The fund is intended to provide exposure to the healthcare sector, primarily through the F/m Emerald Life Sciences Innovation ETF.

TMED No data

Why people hold it

  • LFSC 0.54% buys active healthcare management for less than the median active US equity fund charges, so the stock-picking doesn't start in a fee hole.
  • The portfolio sticks closely to the healthcare mandate in its filings. What the documents describe is what shows up in the holdings.
  • One ticket for a specialist life sciences sleeve run by a manager making calls, rather than a rules-based sector index rebalancing on a calendar.

TMED No data

Worth knowing

  • LFSC Thinly traded, with a modest asset base. Spreads can run wider than on giant sector funds, which makes limit orders and quiet mid-session windows worth the attention.
  • Launched in October 2024, so the track record is short and any read on its risk behavior rests on limited history.
  • This is a total-return vehicle, not an income one. It has not been paying distributions.

TMED No data

Full LFSC profile⁠

Full TMED profile⁠

LFSC vs TMED Holdings

How LFSC and TMED differ

Overlap by weight

4.1%

Shared holdings make up 16.8% of LFSC and 4.1% of TMED.

Level by level

  • Holdings5 in both4.1%
  • Countryby domicile96.1%
  • Asset classEquity100%

Sector

No Sector split for LFSC.

Country, concentration and asset class

Country by domicile

Country weights in LFSC and TMED, widest gap first
CountryMore in LFSCMore in TMED
United StatesLFSC +3.9 points
SwitzerlandTMED +1.8 points
GermanyTMED +0.7 points
CanadaTMED +0.6 points
Other countries (3)TMED +0.8 points

Concentration

Weight in the 10 largest Holdings

  • LFSC54.8%
  • TMED37.0%

Securities held

  • LFSC38
  • TMED110

Asset class

LFSC
Equity
TMED
Equity

Holdings

  • Only in LFSC33
  • In both5
  • Only in TMED105

Only in LFSC

33 securities, 83.2% of LFSC by weight

  • Replimune Group Inc8.66%
  • LivaNova PLC6.87%
  • Cogent Biosciences Inc6.04%

Only in TMED

105 securities, 93.0% of TMED by weight

  • Eli Lilly & Co Common Stock5.94%
  • UnitedHealth Group Inc Common Stock USD.015.20%
  • Alnylam Pharmaceuticals Inc Common Stock USD.013.89%

Weight gaps

All 5 Holdings in both funds, largest gap first.

Holding weights in LFSC and TMED, widest gap first
HoldingMore in LFSCMore in TMED
Travere Therapeutics IncTVTXLFSC +5.55 points
Billiontoone IncBLLNLFSC +4.35 points
Corvus Pharmaceuticals IncCRVSLFSC +1.00 points
Cytokinetics IncCYTKLFSC +0.95 points
Dianthus Therapeutics IncDNTHLFSC +0.88 points

All LFSC holdings⁠All TMED holdings⁠

How we measure overlap

Each holding counts at its smaller weight in the two funds, summed over the full Holdings. Sector, country and asset class use the same rule on each fund’s split. Cash, FX and derivative lines stay out of the counts. Two bond funds get no overlap figure.

LFSC vs TMED Cost

Overpaying LFSC vs TMED

$1,868

On $10,000 over 30 years. 7% growth a year before fees, expense ratio only.

  • LFSC 0.54%

    $10,720

  • TMED 0.44%

    $8,852

$10,000
30 years

Cost over time

  • LFSC 0.54%
  • TMED 0.44%
  • Overpaying
One line per fund, from year 0 to year 30. Use the arrow keys to read each point.$0$2.5K$5K$7.5K$10K$12.5K051015202530LFSC $10,720TMED $8,852

Year by year

YearLFSCTMEDOverpaying
10$971$794$177
20$3,724$3,061$663
30$10,720$8,852$1,868

Expense ratio

  • 0.54%LFSC
  • 0.44%TMED, cheaper
  • Middle half of US Active Sector funds
  • Median 0.61%

TMED 7th cheapest of 35 funds

LFSC 9th cheapest of 35 funds

LFSC vs TMED Dividends

Last 12 months to Oct 30, 2026
Payout (12M)
LFSC None
TMED No data
Last payment
LFSC No data
TMED $0.16
Ex-dividend
LFSC No data
TMED Dec 23, 2025
Paid on
LFSC No data
TMED Dec 26, 2025
Frequency
LFSC No data
TMED Irregular

Distribution history

Per share, 2025 to 2026, same scale for both

LFSCAll LFSC payments⁠

No distribution history available.

TMEDIrregular · 1 paymentAll TMED payments⁠
One bar per payment. 1 payment from 2025 to 2026 YTD. Dec 23, 2025 $0.16. Use the arrow keys to read each point.$0$0.102026YTD

LFSC vs TMED Risk

Fall from peak · 5 years

This chart needs five years of history for both funds.

Risk facts

VolatilityStd dev, 3 years
LFSC 25.9%since Nov 2024TMED 14.7%since Jul 2025
Return per unit of riskSharpe ratio, 3 years
LFSC 1.06since Nov 2024TMED 1.50since Jul 2025
Worst fallMax drawdown, 5 years
LFSC −29.7%since Oct 2024TMED −11.1%since Jun 2025
Market sensitivityBeta, 5 years
LFSC 0.94TMED 0.46

Popular comparisons

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