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PILL

GradeDNew York Stock Exchange Arca

Direxion Daily Pharmaceutical & Medical Bull 3X ETF

Leveraged · Leveraged & Inverse · Direxion · Inception 2017-11-15 · SEC filings

This fund multiplies its index's move each day and resets that multiple daily. Because daily returns compound, its long-run return can differ from the headline multiple.

$16.85−2.14 (−11.27%)

As of Sep 23, 2026, 3:09 PM EDT

Intraday session: down, 67 prints from 18.99 to 16.85. Range 16.59 to 18.97. Use the arrow keys to read each point.$18.00$19.0010 AM12 PM2 PM4 PM
Expense ratio
1.22%
Fund size
$20M
1Y return
+155.1%
Yield · Last 12 months
0.36%
Holdings
50
Volume · 30D
0.1M sh
NAV per share
$18.16
52W range
low $7.06high $24.15

The ETF.net PILL Grade

D

26/ 100

Rank 28 of 31 in 3x Leveraged Long

Confidence Medium

Six-pillar profile for PILL. Scores out of 100: Cost 13, Risk 61, Mission not scored, Tradability 21, Holdings not scored, Durability 25. Strongest: Risk (61). Weakest: Cost (13). Based on 4 of 6 pillars.
F< 25
D≥ 25
C≥ 40
B≥ 55
A≥ 70

Score 26 of 100 sits in the D band. Bands: A ≥ 70, B ≥ 55, C ≥ 40, D ≥ 25, F < 25; the scale skips E.

  • Cost

    What you pay to own it — the expense ratio plus trading frictions, ranked within its category.
    FScore 13
    Category rank27/31 · bottom quartile
  • Mission

    How faithfully it does the job it claims — tracking its mandate or index with minimal slippage.
    Not scored
  • Risk

    How violently it can move — volatility, drawdown depth, and downside capture versus its category.
    BScore 61
    Category rank10/30 · top 33%
  • Tradability

    How cheaply and easily you can get in and out — liquidity, spread, and premium/discount stability.
    FScore 21
    Category rank27/31 · bottom quartile
  • Holdings

    What it actually owns — the quality, breadth, and concentration of the underlying portfolio.
    Not scored
  • Durability

    Whether it will still be here — the fund’s assets, age, flows, and issuer staying power.
    DScore 25
    Category rank27/31 · bottom quartile

Graded as of Sep 22, 2026 · Based on 4 of 6 pillars

Our read on PILL

ETF.net Research

DPharma with the volume knob at 3x. PILL aims for 300% of the daily move in an equal-weighted index of US drugmakers, a rare single-industry leveraged bet where a small-cap counts about as much as a giant. The daily reset makes it a short-horizon tool.

Stated mandate

The fund seeks daily investment results, before fees and expenses, equal to 300% of the performance of the S&P Pharmaceuticals Select Industry Index.

Why people hold it

  1. 01One of the few US funds offering 3x daily exposure to a single industry: it targets 300% of the daily move of the S&P Pharmaceuticals Select Industry Index, with the leverage reset every day.direxion.com
  2. 02The index is modified equal-weighted across the pharmaceutical names in the S&P Total Market Index, so its roughly 50 holdings give mid- and small-cap drugmakers real weight instead of burying them under the mega-caps.finance.yahoo.com
  3. 03Live since 2017 from Direxion, a house built around daily leveraged and inverse funds, so the plumbing has run through several drug-pricing and biotech cycles.direxion.com

Worth knowing

  1. 01At 1.22% a year it costs more than broad-index 3x peers like FAS (0.92%) and UDOW (0.95%). Leverage on a niche industry is priced accordingly.
  2. 02Hold past one day and the math shifts: returns follow the path, and choppy stretches can erode value even if pharma ends up where it started. Direxion states the fund should not be expected to deliver 3x the index's cumulative return beyond a day.direxion.com
  3. 03It is non-diversified and tied to one industry, and it does not trade with the depth of the headline broad-market 3x funds, so spreads and order type matter more on entry and exit.finance.yahoo.com

PILL Holdings

As of Sep 22, 2026, 10:02 PM
Asset class
Stocks
Holdings
50
Top-10 weight
79%
Largest holding
SPSIPH SWAP ASSET LEG (SPSIPHCTL)28.3%

Sectors

  • Health Care100.0%

Geography

  • United States98.27%
  • Ireland1.73%
The fund’s holdings, weight-ordered — page 1 of 5.
#TickerCompanyWeight %SharesMarket valueIn ETFs
001SPSIPH SWAP ASSET LEG (SPSIPHCTL)28.33%2,354$18M1
002SPSIPH SWAP ASSET LEG (SPSIPHJPL)18.05%1,500$12M1
003SPSIPH SWAP ASSET LEG (SPSIPHUBL)14.16%1,177$9M1
004SPSIPH SWAP ASSET LEG (SPSIPHBCL)9.10%756$6M1
005GOLDMAN FINL SQ TRSRY INST 5066.59%4,232,780$4M100
006DREYFUS GOVT CASH MAN INS1.02%652,176$652K108
007AMRXAMNEAL PHARMACEUTICALS INC0.50%15,860$320K129
008XERSXERIS BIOPHARMA HOLDINGS INC0.49%35,485$312K68
009MANEVERADERMICS INC0.48%2,745$310K56
010ANIPANI PHARMACEUTICALS INC0.47%3,870$305K113
011VTRSVIATRIS INC0.44%16,581$284K266
012LLYELI LILLY & CO0.44%243$283K569
013DFTXDefinium Therapeutics, Inc0.44%7,202$283K66
014EWTXEDGEWISE THERAPEUTICS INC0.44%6,305$281K67
015INDVINDIVIOR PHARMACEUTICALS INC0.44%7,869$280K127

Showing 1–15 of 69 holdings

PILL Performance

Shows how $10,000 changes over the selected period, with cash distributions reinvested at the closing price on each ex-dividend date.

PILL$25,507
SPY tracks large US stocks. It provides market context, rather than representing this fund’s strategy, asset class or investment benchmark.$11,723
Sep 22, 2025 to Sep 22, 2026. PILL $25,507. SPY $11,723. Use the arrow keys to read each point.$7,714$20,797$33,879Sep 2025Mar 2026Sep 2026

Sep 22, 2025 – Sep 22, 2026

Returns run to the Sep 22, 2026 close, with cash distributions reinvested. Each period starts on the same date that many months or years earlier. Periods over one year show the average yearly return.

Trailing total return for PILL. Periods over one year show the average yearly return.
PeriodPILL
Year to date+54.7%
1 month−16.8%
3 months+28.3%
1 year+155.1%
3 years+37.3%per year
5 years+2.7%per year
10 yearsFund is under 10 years oldper year

As of the close, with distributions reinvested.

Calendar-year total return with cash distributions hypothetically reinvested at the ex-dividend date’s closing price. The current year shows year to date.

Annual total returns for PILL
YearReturn barPILL
2026 YTD+54.7%
2025+75.1%
2024−7.3%
2023−12.1%
2022−43.2%
2021−37.3%
2020+0.3%

PILL in the news

ETF.net Research hasn’t filed on PILL yet — coverage lands here as it’s written.

PILL Dividends

Adds up every distribution paid per share over the last 12 months, divided by the last completed close. Distributions are counted by ex-date. Data through Sep 22, 2026.
0.36%Last 12 months
Payout per share
$0.07Last 12 months
Last payment
$0.02 per share
Paid on
Shares bought on or after this date do not qualify for this distribution.
Frequency
Quarterly

Distribution history

2017–2026

One bar per payment. 27 payments from 2017 to 2026 YTD. Dec 19, 2017 $0.01; Jun 19, 2018 $0.05; Sep 25, 2018 $0.04; Dec 27, 2018 $0.10; Mar 19, 2019 $0.06; Jun 25, 2019 $0.02; Sep 24, 2019 $0.02; Dec 23, 2019 $0.00033; Dec 21, 2021 $0.00007; Mar 22, 2022 $0.0082; Jun 22, 2022 $0.0036; Sep 20, 2022 $0.02; Dec 20, 2022 $0.03; Mar 21, 2023 $0.02; Jun 21, 2023 $0.05; Sep 19, 2023 $0.04; Dec 21, 2023 $0.04; Mar 19, 2024 $0.03; Jun 25, 2024 $0.02; Sep 24, 2024 $0.03; Dec 23, 2024 $0.01; Mar 25, 2025 $0.02; Jun 24, 2025 $0.02; Sep 23, 2025 $0.0099; Dec 23, 2025 $0.03; Mar 24, 2026 $0.01; Jun 23, 2026 $0.02. Use the arrow keys to read each point.2017201820192020202120222023202420252026YTD
Ex-datePay dateAmount per share
Jun 23, 2026Jun 30, 2026$0.02
Mar 24, 2026Mar 31, 2026$0.01
Dec 23, 2025Dec 31, 2025$0.03
Sep 23, 2025Sep 30, 2025$0.0099
Jun 24, 2025Jul 1, 2025$0.02
Mar 25, 2025Apr 1, 2025$0.02
Dec 23, 2024Dec 31, 2024$0.01
Sep 24, 2024Oct 1, 2024$0.03
Jun 25, 2024Jul 2, 2024$0.02
Mar 19, 2024Mar 26, 2024$0.03
Dec 21, 2023Dec 29, 2023$0.04
Sep 19, 2023Sep 26, 2023$0.04

PILL Risk

This fund targets a multiple of the daily move of its index and resets daily. Hold it longer than one reset and compounding makes the return diverge from that target. In choppy markets it can lose value even when the index ends flat.

How much the fund’s monthly returns vary, scaled to a year.
64.4%
Annualised · 36 months to Aug 2026
How it’s calculated: standard deviation

The sample standard deviation of monthly total returns, multiplied by the square root of 12.

Uses up to 36 complete months, with at least 12 required. Total returns include reinvested distributions.

Return above 3-month US Treasury bills per unit of volatility.
0.65
vs 3-month T-bills · to Aug 2026
How it’s calculated: Sharpe ratio

Subtract each month’s Treasury-bill return from the fund’s monthly total return.

Divide the average of those excess returns by their sample standard deviation, then multiply by the square root of 12.

Uses up to 36 complete months, with at least 12 required. Each month uses the Treasury yield quoted at the end of the previous month.

The largest fall from a peak to the low that followed.
−82.0%
Trough Apr 2025
How it’s calculated: maximum drawdown

The largest percentage decline from an earlier peak, using total returns with reinvested distributions.

Uses up to five years through the last close, with at least 12 months required.

How strongly the fund’s returns move with its asset-class index.
1.76
vs its asset-class index
How it’s calculated: beta

The beta figure is supplied by FMP. The comparison index depends on the fund’s broad asset class.

PILL Cost

Expense ratio1.22%
  • The middle half of 3x Leveraged Long funds
  • Median 0.98%

25 of the 30 3x Leveraged Long funds charge less.

PILL costs $122.00 a year on $10,000. The median 3x Leveraged Long fund costs $98.50.