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PBE

GradeCNew York Stock Exchange Arca

Invesco Biotechnology & Genome ETF

Themes · Invesco · Inception 2005-06-23 · SEC filings

$96.31−1.36 (−1.39%)

As of Sep 23, 2026, 3:10 PM EDT

Intraday session: down, 58 prints from 97.67 to 96.31. Range 96.31 to 97.73. Use the arrow keys to read each point.$96.50$97.00$97.5010 AM12 PM2 PM4 PM
Expense ratio
0.59%
Fund size
$418M
1Y return
+41.0%
Yield · Last 12 months
1.36%
Holdings
31
Volume · 30D
0M sh
NAV per share
$95.91
52W range
low $67.69high $98.82

The ETF.net PBE Grade

C

55/ 100

Rank 8 of 17 in Biotech & Genomics

Confidence High

Six-pillar profile for PBE. Scores out of 100: Cost 19, Risk 60, Mission 91, Tradability 60, Holdings 48, Durability 78. Strongest: Mission (91). Weakest: Cost (19). Leans toward Mission.
F< 25
D≥ 25
C≥ 40
B≥ 55
A≥ 70

Score 55 of 100 sits in the C band. Bands: A ≥ 70, B ≥ 55, C ≥ 40, D ≥ 25, F < 25; the scale skips E.

  • Cost

    What you pay to own it — the expense ratio plus trading frictions, ranked within its category.
    FScore 19
    Category rank14/17 · bottom quartile
  • Mission

    How faithfully it does the job it claims — tracking its mandate or index with minimal slippage.
    AScore 91
    Category rank1/9 · top 11%
  • Risk

    How violently it can move — volatility, drawdown depth, and downside capture versus its category.
    BScore 60
    Category rank8/17 · top 47%
  • Tradability

    How cheaply and easily you can get in and out — liquidity, spread, and premium/discount stability.
    BScore 60
    Category rank6/17 · top 35%
  • Holdings

    What it actually owns — the quality, breadth, and concentration of the underlying portfolio.
    CScore 48
    Category rank13/17 · bottom quartile
  • Durability

    Whether it will still be here — the fund’s assets, age, flows, and issuer staying power.
    AScore 78
    Category rank3/17 · top 18%

Graded as of Sep 22, 2026

Our read on PBE

ETF.net Research

CMost biotech ETFs buy the whole sector. PBE screens it, ranking names on momentum, quality and value, then holding about 30 US biotech and genome stocks. A quant stock-picker wearing index clothing.

Stated mandate

The Fund seeks to track, before fees and expenses, the results of its designated biotechnology and genome benchmark index.

Why people hold it

  1. 01The Intellidex index rates companies on price momentum, earnings momentum, quality, management action and value, then lands on about 30 names. Selection, not sector beta.invesco.com
  2. 02Trading since 2005, it has been through several full biotech boom-and-bust cycles. Long tenure for a thematic fund.invesco.com
  3. 03No mandate drift: the stated job is tracking a US biotechnology and genome index, and the portfolio stays inside that lane.
  4. 04Normally keeps at least 90% of total assets in index securities, so what you see in the methodology is what you own.invesco.com

Worth knowing

  1. 01At 0.58% a year it charges more than the typical biotech ETF, and the big cap-weighted rivals (IBB, XBI, IBBQ) list lower fees. The screen isn't free.
  2. 02Roughly 30 holdings and a non-diversified structure: one bad trial readout lands harder here than in an index spread across hundreds of names.money.usnews.com
  3. 03Thinly traded next to the category's giants, so bid-ask spreads can run wider. Limit orders matter more with a fund like this.

PBE Holdings

As of Sep 20, 2026, 1:47 PM
Asset class
Stocks
Holdings
31
Top-10 weight
47%
Largest holding
NTRA5.7%

Sectors

  • Health Care99.9%
  • Financials0.1%

Geography

  • United States97.25%
  • Netherlands2.75%
The fund’s holdings, weight-ordered — page 1 of 3.
#TickerCompanyWeight %SharesMarket valueIn ETFs
001NTRANatera Inc5.69%63,897$24M223
002ILMNIllumina Inc5.53%95,636$23M305
003GILDGilead Sciences Inc5.24%144,633$22M482
004BIIBBiogen Inc5.07%97,463$21M331
005REGNRegeneron Pharmaceuticals Inc4.89%25,818$20M401
006RPRXRoyalty Pharma PLC4.89%346,648$20M202
007VRTXVertex Pharmaceuticals Inc4.77%38,921$20M417
008AMGNAmgen Inc4.53%48,651$19M470
009NVAXNovavax Inc3.03%1,243,231$13M66
010SRPTSarepta Therapeutics Inc3.01%620,303$12M125
011EXELExelixis Inc2.91%206,910$12M247
012HALOHalozyme Therapeutics Inc2.91%107,360$12M200
013TGTXTG Therapeutics Inc2.91%211,761$12M129
014QGENQIAGEN NV2.81%268,866$12M32
015RGENRepligen Corp2.76%64,594$11M150

Showing 1–15 of 33 holdings

PBE Performance

Shows how $10,000 changes over the selected period, with cash distributions reinvested at the closing price on each ex-dividend date.

PBE$14,100
SPY tracks large US stocks. It provides market context, rather than representing this fund’s strategy, asset class or investment benchmark.$11,723
Sep 22, 2025 to Sep 22, 2026. PBE $14,100. SPY $11,723. Use the arrow keys to read each point.$9,154$11,891$14,629Sep 2025Mar 2026Sep 2026

Sep 22, 2025 – Sep 22, 2026

Returns run to the Sep 22, 2026 close, with cash distributions reinvested. Each period starts on the same date that many months or years earlier. Periods over one year show the average yearly return.

Trailing total return for PBE. Periods over one year show the average yearly return.
PeriodPBE
Year to date+20.2%
1 month+0.1%
3 months+15.3%
1 year+41.0%
3 years+20.2%per year
5 years+5.4%per year
10 years+8.7%per year

As of the close, with distributions reinvested.

Calendar-year total return with cash distributions hypothetically reinvested at the ex-dividend date’s closing price. The current year shows year to date.

Annual total returns for PBE
YearReturn barPBE
2026 YTD+20.2%
2025+24.8%
2024+1.1%
2023+3.7%
2022−10.8%
2021+1.5%
2020+25.7%

PBE in the news

ETF.net Research hasn’t filed on PBE yet — coverage lands here as it’s written.

PBE Dividends

Adds up every distribution paid per share over the last 12 months, divided by the last completed close. Distributions are counted by ex-date. Data through Sep 22, 2026.
1.36%Last 12 months
Payout per share
$1.33Last 12 months
Upcoming payment
$0.02 per share
Pays on
Shares bought on or after this date do not qualify for this distribution.
Frequency
Quarterly

Distribution history

2017–2026

One bar per payment. 14 payments from 2017 to 2026 YTD. Mar 17, 2017 $0.06; Jun 16, 2017 $0.22; Sep 24, 2018 $0.0021; Mar 23, 2020 $0.03; Jun 20, 2023 $0.01; Mar 18, 2024 $0.02; Jun 24, 2024 $0.0082; Mar 24, 2025 $0.03; Jun 23, 2025 $0.13; Sep 22, 2025 $0.23; Dec 22, 2025 $0.42; Mar 23, 2026 $0.08; Jun 22, 2026 $0.81; Sep 21, 2026 $0.02. Use the arrow keys to read each point.2017201820192020202120222023202420252026YTD
Ex-datePay dateAmount per share
Sep 21, 2026Pays Sep 25, 2026$0.02
Jun 22, 2026Jun 26, 2026$0.81
Mar 23, 2026Mar 27, 2026$0.08
Dec 22, 2025Dec 26, 2025$0.42
Sep 22, 2025Sep 26, 2025$0.23
Jun 23, 2025Jun 27, 2025$0.13
Mar 24, 2025Mar 28, 2025$0.03
Jun 24, 2024Jun 28, 2024$0.0082
Mar 18, 2024Mar 22, 2024$0.02
Jun 20, 2023Jun 23, 2023$0.01
Mar 23, 2020Mar 31, 2020$0.03
Sep 24, 2018Sep 28, 2018$0.0021

PBE Risk

How much the fund’s monthly returns vary, scaled to a year.
17.6%
Annualised · 36 months to Aug 2026
How it’s calculated: standard deviation

The sample standard deviation of monthly total returns, multiplied by the square root of 12.

Uses up to 36 complete months, with at least 12 required. Total returns include reinvested distributions.

Return above 3-month US Treasury bills per unit of volatility.
0.73
vs 3-month T-bills · to Aug 2026
How it’s calculated: Sharpe ratio

Subtract each month’s Treasury-bill return from the fund’s monthly total return.

Divide the average of those excess returns by their sample standard deviation, then multiply by the square root of 12.

Uses up to 36 complete months, with at least 12 required. Each month uses the Treasury yield quoted at the end of the previous month.

The largest fall from a peak to the low that followed.
−33.3%
Trough Jun 2022
How it’s calculated: maximum drawdown

The largest percentage decline from an earlier peak, using total returns with reinvested distributions.

Uses up to five years through the last close, with at least 12 months required.

How strongly the fund’s returns move with its asset-class index.
0.79
vs its asset-class index
How it’s calculated: beta

The beta figure is supplied by FMP. The comparison index depends on the fund’s broad asset class.

PBE Cost

Expense ratio0.59%
  • The middle half of Biotech & Genomics funds
  • Median 0.47%

12 of the 15 Biotech & Genomics funds charge less.

PBE costs $59.00 a year on $10,000. The median Biotech & Genomics fund costs $47.00.